24 physically active men took MRI’s Platinum NO2 product or a placebo for 7 days (1). Platinum supplied a total of 12 g of arginine alpha-ketoglutarate (AKG) in the dosage given.
Before and after supplementation, the subjects lifted weights.Various measurements were made, including markers of blood flow and nitric oxide (NO) production.
The result: Supplementing with arginine AKG increased arginine levels (not much of a surprise here), but was no more effective at increasing blood flow and NO production than a placebo. Thus, changes in either were attributed to resistance exercise itself.
Conclusion: The best way to get a pump is to work out. Arginine won’t improve it.
REFERENCE
1. http://www.ncbi.nlm.nih.gov/pubmed/21813912